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Four Leaf RoverPowderDogsLabel verified 2026-10-13

Four Leaf Rover Saccharomyces Boulardii

Four Leaf Rover's Saccharomyces Boulardii is a single-organism powder sold in a 1.8 oz (49.5 g) jar, dosed by fractional teaspoon according to your dog's weight. The label names one strain, Saccharomyces boulardii, with no companion bacteria. The manufacturer's own product-facts label states 40 billion CFU and 1,000 mg of organic inulin per full teaspoon (3.4 g) -- a higher count than older third-party listings show, because Four Leaf Rover's own product photos confirm this is a relabeled, higher-potency version of the same jar. Store it in the fridge; the brand says a cool, dark spot works if fridge space is tight, but refrigeration is the primary instruction, not an alternative.

Label claims include helping maintain a healthy gut during antibiotic use, supporting a healthy gut lining, and having no fillers or dextrins, all the manufacturer's own wording. The label doesn't say whether the 40 billion CFU figure holds through the printed expiry or only at manufacture. We found no ASIN, so there's no confirmed Amazon listing for this exact product, and it shouldn't be confused with Four Leaf Rover's separate multi-strain product, Protect, which uses different organisms and is shelf-stable rather than refrigerated. Dosing runs in four weight brackets from 1 lb up to 91+ lbs, each a different fraction of a teaspoon, built around a single yeast strain rather than a broad bacterial blend.

CFU / tsp40 billionunstated
Strains10 strain-numbered
PrebioticOrganic inulin (from Jerusalem artichoke) — 1,000 mg per tsp (3.4 g)amounts not stated unless quoted
StorageRefrigerate"We recommend keeping all Four Leaf Rover products in the fridge to maintain freshness. But if space is limited, you can store Saccharomyces boulardii in a cool, dark place." (fridge preferred, room-temp acceptable — a preference, not a strict mandate)
Compare with AnimalBiome S. boulardii + FOS Powder Price & availability on Amazon. Commission disclosure in the footer.

What's in it, strain by strain

Transcribed from the guaranteed analysis. "Species only" means this label prints no numbered strain, so study results for a named strain don't transfer.

Organism (as printed)GenusStrain-named?Dog evidence
Saccharomyces boulardiiSaccharomycesSpecies only1 study
Total: 40 billion CFU per tsp.Prebiotics: Organic inulin (from Jerusalem artichoke) — 1,000 mg per tsp (3.4 g)Other ingredients: not stated

Dosing by dog weight (from the label)

1–30 lb0.125 tspper tsp/day
31–60 lb0.25 tspper tsp/day
61–90 lb0.5 tspper tsp/day
Over 91 lb0.75 tspper tsp/day

1-30 lbs: 1/8 tsp daily. 31-60 lbs: 1/4 tsp daily. 61-90 lbs: 1/2 tsp daily. 91+ lbs: 3/4 tsp daily. ASIN not found; do not confuse with Four Leaf Rover's separate multi-strain 'Bifido for Fido' product (ASIN B08X163FG2), which is a different SKU.

Days per pack & cost per day

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Questions people ask about Four Leaf Rover Saccharomyces Boulardii

How much Saccharomyces boulardii is in each dose?

40 billion CFU per full teaspoon (3.4 g), per the manufacturer's current product-facts label.

Does it need to be refrigerated?

The brand's primary instruction is yes, refrigerate -- a cool, dark pantry spot is offered only as a fallback if fridge space is limited.

Why do some other sites list a lower CFU number for this product?

Four Leaf Rover's own product photos show this is a relabeled, higher-potency version of an older jar -- older listings elsewhere are echoing the previous label.

Is this the same as Four Leaf Rover Protect?

No. Protect is a different, multi-organism product (S. boulardii plus two Bacillus strains) and is shelf-stable; this single-strain S. boulardii product is meant to be refrigerated.